Endocrine Abstracts

Objectives: To evaluate the efficacy of growth hormone (GH) treatment in children with Turner syndrome (TS) and to analyze the factors affecting the success of treatment.Methods: Retrospective observational study was conducted for 62 patients with TS. 3 groups of patients were identified: group 1 with karyotype 45, X (n=32), group 2 with mosaic variant 45,X/46,XX (n=8), group 3 with structural anomalies of X chromosome (n=22). ...

Aim: To evaluate bone mineral density (BMD) in children with different karyotype variants of Turner syndrome (TS) depending on the stage and the onset of puberty (spontaneous or induced).Methods: The total studied group consisted of 75 children with TS from 8 to 17 years (mean age 14.2 ± 2.61), who were regularly followed-up in the University hospital (Minsk) and age matched 25 healthy controls. TS was diagnosed according to the results of karyotypi...

IntroductionTurner syndrome (TS) is usually accompanied by hyperhonadotroic hypogonadism and primary amenorrhea due to gonadal disgenesis. One-third of girls with TS have spontaneous thelarhe (ST). Regular menstrual cycles occur in at most 6% of this patients.ObjectivesTo analyze the characteristics of pubertal development in children with different karyotype variants of TS.Methods<...

Introduction: The long-term follow-up of the patients with well-differentiated thyroid cancer (WDTC) includes the monitoring of suppressive levothyroxine therapy. Our study evaluated the peculiarities of thyroid status in WDTC patients on the doses of levothyroxine leading to TSH suppression (lower than 0.5 mI/l).Study design: We have studied 114 patients with WDTC, 24 men and 90 women. The follow-up was a least 10 years after thyroid surgery, mean age a...

A lot of new data have been recently generated regarding the complex relationship between the thyroid function and metabolic parameters.The aim of the study was to estimate the obesity and metabolic syndrome (MS) rates according to the age and the thyroid function in the residents of Belarus.We have examined 894 subjects aged 18–44 years (82.2% females) living in Stolin district, Brest region of Belarus. The endocrinological e...